Marzo 15, 2011 | Por befipetoti | # Enlace permanente
LONDON – With 6.6 million tickets up for sale, two Olympic superstars came to London on Tuesday to help celebrate the countdown to the 2012 Summer Games.
Nine-time track and field gold medalist Carl Lewis and five-time gymnastics champion Nadia Comaneci joined London Olympic organizing committee leader Sebastian Coe — a former Olympian — for a series of events across the capital.
“It’s happening,” said Lewis, the American sprinter and long jumper who competed in four Olympics. “It’s wonderful to get the bid. It’s wonderful to know what’s coming. But today you can actually start your opportunity to be a part of it.”
Tuesday marked the first chance for fans to apply for tickets to the 645 competition sessions across 26 sports, with prices ranging from $32 for some events to $1,200 for the men’s 100-meter final.
Comaneci, the Romanian who scored the first perfect 10.0 in modern Olympic history when she won three golds at the 1976 Montreal Games at age 14, said she looks forward to coming back next year to watch the gymnastics and soak up the atmosphere.
“I always say when the Olympics are happening, you shouldn’t be in any other place in the planet — you should be here,” Comaneci said.
The buildup to the opening ceremony on July 27, 2012, comes with Olympic venues being completed on time and on budget. Britain is spending $15 billion to build new venues and turn an industrial wasteland in east London into a vast Olympic Park.
“This isn’t the finishing straight, but we’re in the back straight of the 800,” said Coe, a former 800-meter record holder who also won two Olympic gold medals in the 1,500 meters.
The top seats for the opening ceremony go for $3,215. Organizers braced for a crush of demand on the online site, even though the tickets are not being sold on a first-come, first-served basis.
Customers can apply for tickets over a six-week period ending April 26, with no advantage to signing up early. Any oversubscribed tickets will be distributed via a ballot, or lottery, system. Tickets will be allocated by June 24.
The first glitch arose a few hours into the ticket launch, when fans with Visa credit cards that expire before the end of August found they were unable to process their orders. Visa is an Olympic sponsor and the only card that can be used to purchase tickets.
“It is an issue with Visa rather than the website or our systems,” officials of London 2012 said.
While demand will be huge for the 100-meter final, Lewis urged fans to consider buying tickets to some of the lower-profile events.
“I’ve been to four Olympic Games since I retired,” he said. “Every time I’ve gone to two new sports that I’ve never seen before. I think it’s a unique opportunity to go see team handball or badminton or volleyball. It gives you the opportunity to experience something else. You may end up watching badminton so much you may end up taking up the sport yourself.”
Organizers are promising packed venues and enthusiastic crowds.
“The athletes enjoy the full stands,” Lewis said. “I remember in Los Angeles in the 100 heats there were 93,000 people there. It makes a huge difference, especially for the home country. It creates a sense of pride.”
Lewis donned a yellow construction hat and jacket to tour the 80,000-seat Olympic Stadium where the track and field events will be contested in 2012. Lewis won four gold medals at the 1984 Los Angeles Olympics, successfully defended his 100-meter title in Seoul in 1988 after Ben Johnson was stripped of the title for doping and won the long jump for a fourth straight time at the 1996 Atlanta Games.
“I’m a long jumper that sprinted,” Lewis said. “Everyone says ‘fastest man in the world.’ Yeah, I was that, too. I was able to win four in a row in the long jump. I take the most pride in that. To come back and be the first one to actually win back-to-back and then do it four time2C it was just tremendous.”
The sport’s greatest athlete since Lewis is Usain Bolt, the Jamaican sprinter who swept the 100, 200 and 4×100 relay at the 2008 Beijing Olympics in world-record times. A year later, Bolt again set world records in the 100 and 200 at the world championships in Berlin.
Can Bolt defend his Olympic titles in London?
“The opportunity is there,” Lewis said. “It’s very, very difficult, as I know, to win back-to-back at the Olympics. So many things have to happen for you to win once, let alone twice, so good luck to him.”
But Lewis is cheering for American sprinter Tyson Gay, who beat Bolt in Stockholm last year and has the second fastest time ever in the 100 (9.69 seconds) behind the Jamaican’s 9.58.
“I think its going to be a tremendous race,” Lewis said. “I went to two Olympic finals and you never know what’s going to happen. Usain has run tremendously. He’s the best in the world right now, but Tyson’s going to give him a run for his money.”
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ZURICH (Reuters) – Novartis AG's blood cancer drug INC424 could rake in annual sales of $1 billion, the group's head of oncology told Reuters on Tuesday, in a boost to the Swiss drugmaker's cancer pipeline.
“We believe it can become a very reasonable commercial opportunity” said Herve Hoppenot, president of Novartis Oncology.
Earlier on Tuesday, Novartis said a late-stage trial had shown INC424, which Novartis is developing with Incyte, significantly reduced the spleen size of patients with myelofibrosis (MF) when compared with the best available therapy.
MF is a rare condition in which abnormal bone marrow stem cells are produced, resulting in the growth of connective tissue fibers. A reduction in the spleen size is a measurement for clinical improvement in this disease.
Novartis, which has rights to the drug outside of the United States, is aiming for annual sales in MF of more than $500 million.
Revenue could rise to $1 billion if the use of the drug is widened to include other indications such as polycythemia vera (PV), a rare blood disorder that in a very small number of cases can progress to leukemia.
Novartis is aiming to launch the drug in 2012.
Novartis shares closed 1.2 percent weaker after paring some of the days earlier losses.
Novartis said the results supported results from another Phase III trial conducted by Incyte, which said in December it expects to launch the drug by the end of 2011.
Incyte said on Tuesday its U.S. new drug application submission was on track for the second quarter of the year.
The drug — a janus kinase (JAK) inhibitor — belongs to the same class as Pfizer's high-profile experimental medicine tofacitinib, which is being developed for the bigger market in treating rheumatoid arthritis and is one of the most important in the U.S. company's pipeline.
“INC424 is highly synergistic with Novartis's hematology franchise based on Glivec and follow-on drug, Tasigna, and as such is set to leverage the substantial profit generation of this all-important product line,” Helvea analysts said in a note.
“We currently carry $660 million peak sales in our model although the potential of the drug in the Novartis territories could be well in excess of $1 billion as we believe that MF and PV remain substantially under-diagnosed,” the analysts said.
(Editing by Hans Peters and Andrew Callus)
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TUESDAY, March 15 (HealthDay News) — Guidelines for children's heart
and breathing rate reference ranges need to be updated, say researchers
who reviewed 69 studies that included a total of about 143,000
children.
The review produced new reference ranges that differ widely from
existing published guidelines, according to Dr. Matthew Thompson, of
Oxford University in the United Kingdom, and colleagues. The reference
ranges are used for assessing and resuscitating children.
The new reference ranges show declines in respiratory rate from birth
to early adolescence, with the steepest decrease in infants under 2 years
of age — falling from a median of 44 breaths per minute at birth to 26
breaths per minute at 2 years of age.
The researchers also found that median heart rate increases from 127
beats per minute at birth to a maximum of 145 beats per minute at about 1
month, and then decreases to 113 beats per minute at 2 years of age.
In many cases, the rates in the review are completely different from
the existing published ranges. For example, the existing reference range
classifies about half of healthy 10-year-olds as having an abnormal heart
or respiratory rate, the researchers said.
“Our centile charts of respiratory rate and heart rate in children
provide new evidence-based reference ranges for these vital signs. We have
shown that there is substantial disagreement between these reference
ranges, and those currently cited in international pediatric guidelines,”
they concluded.
“For clinical assessment of children, our findings suggest that current
consensus-based reference ranges for heart rate and respiratory rate
should be updated with new thresholds on the basis of our proposed centile
charts, especially for those age groups where there are large differences
between current ranges and our centile charts, indicating that many
children are likely to be misclassified.”
The review findings are published in the March 15 online edition of
The Lancet.
Dr. Rosalind L. Smyth of the Institute of Translational Medicine in
Liverpool, U.K., said she was surprised the study does not include
differences between sexes; she also warned that factors such as pain or
distress can raise heart rate.
“[These] centile charts should initiate important new studies to
establish where the clinical boundaries should be set for different ages,
to assist clinicians to distinguish between normal and abnormal heart and
respiratory rates,” she said in a commentary accompanying the study.
“[They] will then need to be extensively validated in different settings
and populations before they can be incorporated into clinical
practice.”
More information
The American Heart Association outlines ways to keep kids healthy.
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Bienvenid@ a Blogs de la Gente. Este es tu primer posteo y es un ejemplo. Podés editarlo o borrarlo y escribir uno nuevo. Gracias por participar en la comunidad de Blogs de la Gente. ¡Feliz blogueo!
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Mexico City – An apology is not enough for Guatemalans deliberately infected with syphilis by a US medical team in the 1940s. Five months after the American taxpayer-funded medical experiment came to light, victims have brought a class-action lawsuit against the US government seeking compensation for resulting health problems.
Seven named plaintiffs, which include both victims and heirs living in Guatemala, filed the lawsuit Monday in a Washington, D.C., district court on behalf of 700 Guatemalan soldiers, mental health patients, and orphans. The victims were all secretly experimented on from 1946 to 1948, the complaint says.
The experiments were “both unprecedented and unequivocally impermissible in the United States and throughout the civilized world,” the complaint states.
The court brief charges that US public health doctors hired prostitutes diagnosed with syphilis or gonorrhea to have sexual relations with soldiers, prison inmates, and psychiatric patients in Guatemala with the intention of spreading the disease. Once the unknowing subjects were diagnosed with illnesses, the US medical team tested them for potential cures, including penicillin. Orphaned Guatemalan children as young as 6 years old were used as an uninfected test group, according to the suit.
IN PICTURES: Mexico's drug war
The US government apologized to Guatemala in October when the six-decade-old project was first revealed in a policy journal, calling the experiments “clearly unethical” and condemning the “appalling violations” of medical ethics and human decency. Both the US and Guatemalan governments announced investigations into the case.
But when victims’ lawyers contacted the Department of Justice to negotiate a solution last week, they received no reply, say the attorneys of Florida-based Conrad & Scherer and New York-based Parker Waichman Alonso.
The Justice Department said the government will review the complaint to determine how it will respond. Spokesman Charles Miller said he could not say whether his office had discussed a settlement with the plaintiffs' lawyers since the matter is now in litigation. The US Department of Health and Human Services, the main defendant named in the case, did not comment.
The complaint compares the victims to those of the 1930s Tuskegee syphilis experiments in Alabama, where hundreds of poor African Americans were observed for decades without being told they had the disease. The same Public Health Service doctors from the Tuskegee case had even initially supervised the Guatemalan experiments, according to Piper Hendricks of Conrad & Scherer.
The lawsuit demands punitive damages to be decided by the court. While damages are hard to predict, Ms. Hendricks says juries have granted large awards in similar Alien Tort Statute cases, where human rights violations were committed by US citizens in a foreign country. She pointed to the 2010 “Chuckie Taylor” case, where a US citizen charged with torture in Liberia was found liable for over $20 million in damages.
Hendricks acknowledged, however, that US judges have grown reluctant to take on class actions. She says she’ll have to show strong similarities among victims of the class, many of whom she hopes will join the suit now that it has been filed.
“If there was any question, which I don’t think there was, as to whether nonconsensual human medical experimentation was acceptable, [the] Nuremberg [Trials] answered that loud and clear. And here we were across the ocean continuing this type of experimentation,â€
IN PICTURES: Mexico's drug war
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